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Liver Metabolism and Toxic Byproducts The liver plays a vital role in metabolizing both alcohol and acetaminophen

However, its appetite-suppressing effects gradually wane, leading to a weight-loss plateau despite the mice remaining obese

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Am J Physiol Regul Integr Comp Physiol 306(5):R352R362 Carmody JS et al (2016) Peripheral, but not central, GLP-1 receptor signaling is required for improvement in glucose tolerance after Roux-en-Y gastric bypass in mice

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